Mood Emot 2021 Jul; 19(2): 64-73   https://doi.org/10.35986/me.2021.19.2.64
Predictors of 1-Year Rehospitalization for Patients with Major Depressive Disorder: A Retrospective Study in a University Hospital
Ji-Min Yoo , MD, Sung-Min Kim , MD, Yoo-Hyun Um , MD, Tae-Won Kim , MD, Ho-Jun Seo , MD, Seung-Chul Hong , MD, Jong-Hyun Jeong , MD
Department of Psychiatry, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
Correspondence to: Jong-Hyun Jeong, MD
Department of Psychiatry, The Catholic University of Korea, St. Vincent’s Hospital, 93 Jungbu-daero, Paldal-gu, Suwon 16247, Korea
TEL +82-31-249-7150 FAX +82-31-248-6758 E-mail anton3@catholic.ac.kr ORCID https://orcid.org/0000-0003-3570-7607
Received: June 4, 2021; Revised: July 6, 2021; Accepted: July 6, 2021; Published online: July 31, 2021.
© Korean Society for Affective Disorders. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: This study aimed to assess the clinical characteristics of patients with major depressive disorder who were rehospitalized within 1 year and to determine whether the 1-year rehospitalization rate varied depending on the type of medication and treatment method.
Methods: Clinical characteristics of 531 patients hospitalized for major depressive disorder were assessed. The use and type of antidepressants, antipsychotics, mood stabilizers, and hypnotics were also evaluated.
Results: Of the 531 subjects, 68 (12.8%) were rehospitalized within a year. The number of past depressive episodes (1.56±2.67 vs. 0.90±1.18) (p=0.048) and the number of previous psychiatric hospitalizations (0.82±1.93 vs. 0.29±0.83 times) (p=0.029) were high in the 1-year rehospitalization group. The rate of family history of mood disorder (25.0% vs. 13.6%) (p=0.014) and the rate of comorbid personality disorder (16.2% vs. 8.6%) (p=0.049) were also high in the 1-year rehospitalization group. Multiple logistic regression analysis showed that the number of previous psychiatric hospitalizations affected the rate of 1-year rehospitalization (p=0.003).
Conclusion: The number of previous psychiatric hospitalizations could be used to predict rehospitalizations of patients with major depressive disorder within 1 year. In addition, family history of mood disorders and comorbidity of personality disorders may affect rehospitalization of such patients.
Keywords: Major depressive disorder; Patient readmission; Antidepressants


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