Mood Emot 2022 Mar; 20(1): 8-14   https://doi.org/10.35986/me.2022.20.1.8
Relationship between Depression and Glycated Hemoglobin: Analysis Based on the 2019 Korea National Health and Nutrition Examination Survey
Hye Won Kim, MD1 , Mi Kyoung Seo, PhD2 , Taekjoong Kim, MD, PhD3,4 , Sung Woo Park, PhD2,5,6 , Jung An Lee, MD1 , Jung Goo Lee, MD, PhD1,2,6
1Department of Psychiatry, Haeundae Paik Hospital, Inje University College of Medicine, 2Paik Institute for Clinical Research, Inje University, 3Department of Humanities and Social Sciences in Medicine, Inje University College of Medicine, 4The Iinstitute for Medical Humanities, Inje University College of Medicine, 5Department of Convergence Biomedical Science, Inje University College of Medicine, 6Department of Health Science and Technology, Graduate School, Inje University, Busan, Korea
Correspondence to: Jung Goo Lee, MD, PhD
Department of Psychiatry, Haeundae Paik Hospital, Inje University College of Medicine, 875 Haeun-daero, Haeundae-gu, Busan 48108, Korea
TEL +82-51-890-6749 FAX +82-51-894-6709 E-mail iybihwc@naver.com ORCID https://orcid.org/0000-0003-3393-2667
Received: February 15, 2022; Accepted: March 13, 2022; Published online: March 31, 2022.
© Korean Society for Affective Disorders. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The goal of this study is to investigate the relationship between depression and glycated hemoglobin in the general Korean population.
Methods: Adults aged 19 to 80 years were surveyed as part of the 2019 Korea National Health and Nutrition Examination Survey. A total of 4,831 people were chosen to complete the health questionnaire, provide their body mass index, and get a HbA1c blood test. The general characteristics of groups with high and low glycated hemoglobin were identified. To find out the correlation between depression diagnosis and the general population with high glycated hemoglobin, a chi-square test was carried out. A t-test was also used to compare the means of glycated hemoglobin between the groups diagnosed with and not diagnosed with depression. In analyzing the relationship between depression and glycated hemoglobin, analysis of covariance was performed by adjusting the effects for demographic factors.
Results: Sex, age, income level, education level, drinking, smoking, exercise, and body mass index are all factors that influence glycated hemoglobin. The mean glycated hemoglobin was high in the group diagnosed with depression. The relationship between depression and glycated hemoglobin could not be confirmed using logistic regression after controlling for confounding variables.
Conclusion: There was no significant correlation between depression and glycated hemoglobin in the general population of Korea based on the results of this study.
Keywords: Depression; Glucose; Hemoglobin; Korea National Health and Nutrition Examination Survey


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